Abstract: For the distance between the drive motor and roll of a rolling mill is long and the rigid of its spindle is limited, the normal control of current and speed closed loops leads easily to the phenomena of electromechanical vibration and broken strip as the strip is rolled at high speed. In order to solve the problem, aiming at the characteristics of the approximate model of a main drive system, the uncertain external load disturbance and unmodeled dynamics were regarded as one integrated disturbance. Electromechanical vibration controllers were designed based on extended state observer (ESO) and auto-disturbance-rejection control (ADRC) technology respectively. Simulated results show that the two controllers effectively improve the performances of command following, electromechanical vibration suppression, and robustness to parameter variation. ESO and ADRC were utilized in electromechanical vibration control of the main drive system of a rolling mill, their validity and superiority were verified in comparison with the conventional PI controller and the state feedback controller based on reduced-order state observer.