Abstract: Topology optimization based on a homogenization method was applied to the articulated body of an articulated dump truck under multiple loading cases. The uncertainty of weights and the reliability of experts were taken into consideration when the weights were determined under multiple loading cases. An uncertain quantified expression of the experts' advices was set up by means of the blind number theory, and the weights under every loading case were got and applied to topology optimization under multiple loading cases. Finally, the reliability of the articulated body was analyzed. The rationality of the way to get the weights based on the blind number theory was also proved.